University of Basrah
  • Register
  • Login
  • العربیة

The Medical Journal of Basrah University

Notice

As part of Open Journals’ initiatives, we create website for scholarly open access journals. If you are responsible for this journal and would like to know more about how to use the editorial system, please visit our website at https://ejournalplus.com or
send us an email to info@ejournalplus.com

We will contact you soon

  1. Home
  2. Volume 30, Issue 1
  3. Authors

Current Issue

By Issue

By Subject

Keyword Index

Author Index

Indexing Databases XML

About Journal

Aims and Scope

Editorial Board

Advisory Board

Editorial Staff

Facts and Figures

Publication Ethics

Indexing and Abstracting

Related Links

Peer Review Process

News

LOCAL AND SYSTEMIC IMMUNE RESPONSES IN RATS INFECTED WITH GIARDIA LAMBLIA

    Maha K. Al-Malak Wafaa S. Shani Entehaa Abd-Al-Zahra

The Medical Journal of Basrah University, 2012, Volume 30, Issue 1, Pages 60-73
10.33762/mjbu.2012.64054

  • Show Article
  • Download
  • Cite
  • Statistics
  • Share

Abstract

Objectives: This study was performed to determine the local (tissue) and systemic immune responses in
rats infected with Giardia lamblia.
Materials and methods: Rattus noruigicus rats aged 2 months were inoculated with 103 Giardia lablia cyst.
After 7 and 14 days of infection samples (blood and small intestine) collected from both control and infected rats.
Local immune response was assessed by counting the inflammatory cells in small intestine, mast cell number and
lymph node diameter. Whearas systemic immune response was carried out by measurement of total and differential
WBC count, phagocytic activity of polymphonuclear cells by NBT stain and histamine levels in blood plasma by
ELISA kit.
Results: Results showed an infiltration of inflammatory cells in all parts of small intestine and an increasing in
lymph nodules diameter. Also, there is an infiltration of mast cells. Results of systemic immune response revealed a
high significant differences in total and differential WBC count between two studied groups. Moreover, there was an
increasing in phogocytic activity of polymorphonuclear cells and histamine plasma levels.
Conclusion: Recent data indicated that there is a local and systemic immune response during acute phase of
Giardia lamblia infection in experimental animals.
Keywords:
    immune responses Giardia lamblia experimental animals Histamine
  • PDF
  • XML
(2012). LOCAL AND SYSTEMIC IMMUNE RESPONSES IN RATS INFECTED WITH GIARDIA LAMBLIA. The Medical Journal of Basrah University, 30(1), 60-73. doi: 10.33762/mjbu.2012.64054
Maha K. Al-Malak; Wafaa S. Shani; Entehaa Abd-Al-Zahra. "LOCAL AND SYSTEMIC IMMUNE RESPONSES IN RATS INFECTED WITH GIARDIA LAMBLIA". The Medical Journal of Basrah University, 30, 1, 2012, 60-73. doi: 10.33762/mjbu.2012.64054
(2012). 'LOCAL AND SYSTEMIC IMMUNE RESPONSES IN RATS INFECTED WITH GIARDIA LAMBLIA', The Medical Journal of Basrah University, 30(1), pp. 60-73. doi: 10.33762/mjbu.2012.64054
LOCAL AND SYSTEMIC IMMUNE RESPONSES IN RATS INFECTED WITH GIARDIA LAMBLIA. The Medical Journal of Basrah University, 2012; 30(1): 60-73. doi: 10.33762/mjbu.2012.64054
  • RIS
  • EndNote
  • BibTeX
  • APA
  • MLA
  • Harvard
  • Vancouver
  • Article View: 243
  • PDF Download: 116
  • LinkedIn
  • Twitter
  • Facebook
  • Google
  • Telegram
  • Home
  • Glossary
  • News
  • Aims and Scope
  • Privacy Policy
  • Sitemap

 

 
This journal is licensed under a Creative Commons Attribution 4.0 International (CC-BY 4.0)

Powered by eJournalPlus