EFFECT OF VITEX AGNUS-CASTUS EXTRACT ON SOME PHYSIOLOGICAL PARAMETERS OF MICE (MUS MUSCULUS L.)
The Medical Journal of Basrah University,
2007, Volume 25, Issue 2, Pages 57-59
10.33762/mjbu.2007.48269
Abstract
ABSTRACTVitex (known locally as kaf murium) has along history of traditional use in women. The effect of alcoholic extract of
vitex agnus-castus was examined for its effect on some blood parameters in mice (Mus Musculus). Mice in the
treatment groups were injected intraperitoneally with two doses (6 mg and 12 mg / mouse) of vitex extract while the
control group received distilled water daily for two weeks. Blood parameters (RBC, Hb, PCV) showed a significant
decrease with both doses in comparison to the control group (P<0.01), while no significant decrease in (WBC) was
found. Biochemical parameters (total serum protein, total serum cholesterol) showed a significant decrease in the
treatment groups as compared with the control group (P<0.01). In conclusion, vitex agnus-castus alcoholic extract
can have a significant adverse effect on blood. Its cholesterol lowering effect worths investigation in the future.
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