Abstract
Lymphoid malignancies are the most common primary orbital tumours but they constitute only 2% of extranodal lymphomas. A fifty-year-old lady known case of SS presented with progressive blurred vision and left deep orbital pain for about 5 months duration, with time, she started to develop left eye protrusion with ophthalmoplegia.
The histopathological diagnosis was a low-grade follicular (nodular) B cell subtype of non-Hodgkin lymphoma (Grade 2). Immunohistochemically, it displayed CD45 and CD20 positive, stained whole neoplastic variables sizes follicles, CD3 stained rime of non-neoplastic T cells around the follicles.
Positron Emission Scan (PET scan) exhibited mild hyper-metabolic multiple right cervical and supraclavicular lymph nodes. Moderately hypermetabolic enlarged abdominal (Left Para-aortic, bilateral common iliac, right external and inguinal lymph nodes). The patient after the 4th cycle of chemotherapy has no palpable cervical lymphadenopathy and restores normal vision in the left eye.
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