University of Basrah
  • Register
  • Login
  • العربیة

The Medical Journal of Basrah University

Notice

As part of Open Journals’ initiatives, we create website for scholarly open access journals. If you are responsible for this journal and would like to know more about how to use the editorial system, please visit our website at https://ejournalplus.com or
send us an email to info@ejournalplus.com

We will contact you soon

  1. Home
  2. Volume 37, Issue 2
  3. Authors

Current Issue

By Issue

By Subject

Keyword Index

Author Index

Indexing Databases XML

About Journal

Aims and Scope

Editorial Board

Advisory Board

Editorial Staff

Facts and Figures

Publication Ethics

Indexing and Abstracting

Related Links

Peer Review Process

News

The effect of Lactobacillus plantarum on expression of biofilm genes of Streptococcus mutans isolated from dental caries

    Zahra Saeed Basil Abbas Rasha Othman

The Medical Journal of Basrah University, 2019, Volume 37, Issue 2, Pages 91-99
10.33762/mjbu.2019.163359

  • Show Article
  • Download
  • Cite
  • Statistics
  • Share

Abstract

Background: Dental caries and decay caused by Streptococcus mutans. Sucrose, stimulates S. mutans to yield insoluble glucans to form oral biofilm also called dental plaque to start process of caries. The GtfB and LuxS genes of S. mutans are responsible for development and evolution of biofilm. Lactobacillus plantarum as probiotic can affect the biofilm formation of S. mutans.Aim of the study: To evaluate the effect of Lactobacillus plantarum against S. mutans biofilm formation.Results: Growing biofilm in the presence of sucrose was detected using 100 well microtiter plate crystal violet assay and biofilm formation by S. mutans in the presence of Lactobacillus was detected. Gene expression of biofilm forming genes (GtfB and LuxS) was quantified through Real- time PCR. The transcriptional levels of GtfB and LuxS genes were remarkably down regulated 9.43 -and 4.24- fold change, respectively, when treated with lactobacillus plantarum in comparison with the control group.Conclusions: Lactobacillus plantarum as probiotics can be used effectively to reduce the chance of dental caries by decreasing the effects of S. mutans and their gene expression to conserve good oral health
Keywords:
    Lactobacillus plantarum goat raw milk biofilm Streptococcus mutans
  • PDF (788 K)
  • XML
(2019). The effect of Lactobacillus plantarum on expression of biofilm genes of Streptococcus mutans isolated from dental caries. The Medical Journal of Basrah University, 37(2), 91-99. doi: 10.33762/mjbu.2019.163359
Zahra Saeed; Basil Abbas; Rasha Othman. "The effect of Lactobacillus plantarum on expression of biofilm genes of Streptococcus mutans isolated from dental caries". The Medical Journal of Basrah University, 37, 2, 2019, 91-99. doi: 10.33762/mjbu.2019.163359
(2019). 'The effect of Lactobacillus plantarum on expression of biofilm genes of Streptococcus mutans isolated from dental caries', The Medical Journal of Basrah University, 37(2), pp. 91-99. doi: 10.33762/mjbu.2019.163359
The effect of Lactobacillus plantarum on expression of biofilm genes of Streptococcus mutans isolated from dental caries. The Medical Journal of Basrah University, 2019; 37(2): 91-99. doi: 10.33762/mjbu.2019.163359
  • RIS
  • EndNote
  • BibTeX
  • APA
  • MLA
  • Harvard
  • Vancouver
  • Article View: 421
  • PDF Download: 361
  • LinkedIn
  • Twitter
  • Facebook
  • Google
  • Telegram
  • Home
  • Glossary
  • News
  • Aims and Scope
  • Privacy Policy
  • Sitemap

 

 
This journal is licensed under a Creative Commons Attribution 4.0 International (CC-BY 4.0)

Powered by eJournalPlus