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Incidence and predictors of acute kidney injury among hospitalized patients with COVID-19 infection

    Hayder Aledan Shawqi Azeez Abdali Shannan Ammar Husaini Muqtader Abdulhussein

The Medical Journal of Basrah University, 2020, Volume 38, Issue 2, Pages 37-45
10.33762/mjbu.2020.128481.1038

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Abstract

Abstract
Background and objectives: Acute kidney injury (AKI) may occur in the setting of COVID-19 infection and associated with worse outcome. We aimed to estimate the incidence of AKI among hospitalized patients with COVID-19 infection.
Methods: We conducted an observational cohort study on 339 hospitalized patients with COVID-19 infection at Basra teaching hospital for two months. We studied the rate of AKI, requirement for renal replacement therapy (RRT) and in-hospital mortality.
Results: Among 339 hospitalized patients, AKI was reported in 54 (16%). The peak stages of AKI were stage 1 in 42.6%, stage 2 in 22.2% and stage 3 in 35.2%. AKI was primarily seen in patients with shock on vasopressors in 64.8% and in patients on mechanical ventilation in 25.9%. Increased age, obesity, hypertension, vasopressors and mechanical ventilation were independent risk factors for development of AKI. Among the 54 patients with AKI, 20 patients (37%) required renal replacement therapy (RRT). Sixteen out of 20 patients (80%) of those who required RRT died and only 5 out of 34 patients (15%) of those not required RRT died with a totally mortality in AKI patients of 21 patients (39%).
Conclusions: AKI occurs in patients with COVID-19 disease especially in ICU in association with vasopressors use and mechanical ventilation and is associated with poor prognosis.
Keywords:
    Covid_19 acute kidney injury intensive care unit Mechanical ventilation vasopressors
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(2020). Incidence and predictors of acute kidney injury among hospitalized patients with COVID-19 infection. The Medical Journal of Basrah University, 38(2), 37-45. doi: 10.33762/mjbu.2020.128481.1038
Hayder Aledan; Shawqi Azeez; Abdali Shannan; Ammar Husaini; Muqtader Abdulhussein. "Incidence and predictors of acute kidney injury among hospitalized patients with COVID-19 infection". The Medical Journal of Basrah University, 38, 2, 2020, 37-45. doi: 10.33762/mjbu.2020.128481.1038
(2020). 'Incidence and predictors of acute kidney injury among hospitalized patients with COVID-19 infection', The Medical Journal of Basrah University, 38(2), pp. 37-45. doi: 10.33762/mjbu.2020.128481.1038
Incidence and predictors of acute kidney injury among hospitalized patients with COVID-19 infection. The Medical Journal of Basrah University, 2020; 38(2): 37-45. doi: 10.33762/mjbu.2020.128481.1038
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