Keywords : survival

One-year survival of children with malignant diseases in Basrah

OS. Habib; Ali H. Atwan

The Medical Journal of Basrah University, 2017, Volume 35, Issue 1, Pages 1-10
DOI: 10.33762/mjbu.2017.125131

Background: Childhood cancer represents an important health problem in Basrah with an incidence rate as high as rates in western countries. Little is known about the prognosis and survival of children diagnosed with malignancy after initiation of treatment.
Objectives: to estimate the one-year survival of children diagnosed with malignant diseases in Basrah and to identify non–medical risk factors for the risk of death during the first year following diagnosis.
Methods: This is a hospital-based follow up study of 352 children aged less than 15 years diagnosed with any sort of malignant disease. The study was conducted in Basrah Specialized Hospital for Children over the period (1st of October 2012 to 31st December 2013) and enrolled all newly diagnosed cases during two calendar years (2011-2012 inclusive). The fate of each and every case was ascertained chronologically during and at the end of the 12 months after diagnosis.
Results: The results showed that, of the 352 cases followed up, 102 ( 29.0%) completed their treatment courses at the end of 1st year while 105 (29.8 %) of them were still continuing on treatment , 19 (5.4%) relapsed and still on treatment and 89 ( 25.3 %) of the cases died by the end of first year. The remaining have stopped treatment 25 ( 7.1% ), refused treatment in Basrah 10 ( 2.8% ) or transferred elsewhere on medical advice 2 (0.6%).
The one year survival rate for all the studied children was 74.7%, Thus the one year mortality was 25.3%). Among a set of variables, three "female gender, better mother education and modern type of family accommodation" were significant predictors of one year survival of a child with cancer.
Conclusions: Childhood cancer is major health problem in Basrah in terms of incidence and burden on the health care system. Despite all efforts the one year survival rate was much lower than corresponding figures in many other countries.

Survival of preterm babies beyond the neonatal period

Lamis Aziz Hameed

The Medical Journal of Basrah University, 2016, Volume 34, Issue 2, Pages 101-106
DOI: 10.33762/mjbu.2016.117212

Background: Preterm birth is a significant cause of infant deaths particularly during the neonatal period. Study of these births may assist in predicting the survival of those born preterm, and in turn may help in reducing the causes and undesired outcomes.
Objective: This study was designed to explore the chance of survival among babies admitted to intensive care units in Basrah Maternity and Children Hospital.
Method: The study was a follow up study carried out on 440 babies who were born preterm and were admitted for reasons related to their prematurity to neonatal intensive care units in Basrah maternity and children hospital in 2012, of whom 408 were successfully followed up until the end of the neonatal period (birth to 28 days).
Results: Most of the babies were males (58.8%), singleton (93.1%), delivered by normal vaginal delivery (74.01%), moderately preterm (53.4%) and of birth weight range 1500- < 2500 grams(62.5%). Logistic regression analysis to identify independent predictors of survival showed that neonatal outcome (the probability of surviving the neonatal period) was significantly and independently related to birth weight and gestational age. Other variables [sex, type of delivery and type of birth(single, twin and multiple] could not significantly predict survival in the present study.
Conclusions: It is concluded that the problem of neonatal mortality in Basrah is similar to that reported for other developing and neighboring countries. In our study the neonatal mortality rate was 27.94%, mostly in the first 24 hours of life. Two significant predictors could be identified as undesired predictors of survival; namely; low birth weight and shorter gestational age. We highly recommend a larger scale study on issue of neonatal survival. Perhaps improved care of mothers and neonates reduce the risk of both preterm birth and neonatal death.